Setup
Set Up IM Accounts
After creating your account, you'll be asked to Set Up Instant Messaging as seen below:

Input your IM account for each service, then press Next. You can
add IM accounts later, so feel free to leave any (or all)
blank.
Tip: Each IM account you add will get a dedicated icon at the
top of your contact list for controlling the connection.
Set Up Social Networks

Sign in to each social network. When you're done, press Next.
You can add social networks at any time, so feel free to skip any
(or all) for now.
Tip: Each social network you add will get a dedicated icon at
the top of your contact list for controlling the connection, as
well as a shortcut in your Windows system icon tray
(clock).
Set Up Mail
Trillian is an email client capable of connecting to your mail account via industry standard POP3 or the newer IMAP. You can add your mail account on the following screen, or at any later time:

Important Tip: Trillian automatically checks mail for
Gmail, Windows Live, Yahoo! Mail, and AOL if you
have added IM accounts for those respective services. Do not add
those accounts here. 1. Choose IMAP or POP3.
Check your mail host; most provide instructions. Try googling POP3
Comcast or IMAP Comcast, for example.
2. Input your full email address.
3. Your username is probably the part of your
username before the @ sign, but sometimes it is your full email
address.
4. Type the password you use to get your
email.
5. Your mail server. Most ISPs use
mail.something.com or pop.something.com.
Tip: Don't enter your SMTP server, that's for outgoing email.
6. Use port 110 for POP3, port 143 for IMAP.
When you are done, click Next. Your email account
should now appear in the "Mail" section of your contact list!
End of the setup section
You're all set up!
Congratulations, you're now ready to start using Trillian. If
you've connected to at least one IM network, you should start to
see any online contacts appear in your contact list. If you've
connected to social networks, you'll see their entries appear in
your contact list and also in your system tray (next to your
Windows taskbar clock).
We recommend you read the rest of this guide to get familiarized
with Trillian.
Thanks, from the entire Cerulean Studios team ...
Have fun!